The Structure and Enzyme-Coenzyme Relationship of Supernatant Aspartate Transaminase after Dye Sensitized Photooxidation

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The structure and enzyme-coenzyme relationship of supernatant aspartate transaminase after dye sensitized photooxidation.

Photooxidation of supernatant glutamate aspartate transaminase, limited to the stage during which much of the enzyme activity and only histidine residues are destroyed, does not induce gross protein structural changes as judged by ultracentrifugation, optical rotatory dispersion in the ultraviolet region, and microcomplement fixation techniques. Photooxidized apoenzyme has been shown to bind at...

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ژورنال

عنوان ژورنال: Journal of Biological Chemistry

سال: 1970

ISSN: 0021-9258

DOI: 10.1016/s0021-9258(18)63335-6